FDA Approves Revolution Plus

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FDA Approves Revolution Plus
Posted on February 28, 2019 in News, Products

The U.S. Food and Drug Administration (FDA) has approved Revolution® Plus (selamectin and sarolaner topical solution), a new combination topical product providing 6-in-1 parasite protection against fleas, ticks (Black-legged or deer tick, Gulf Coast tick, and American dog tick), ear mites, roundworms, hookworms and heartworms for cats and kittens as young as eight weeks of age and weighing 2.8 pounds or greater. Revolution Plus combines the proven broad-spectrum protection of selamectin with the advanced flea- and tick-killing power of sarolaner. This first-of-its-kind, next-generation product exemplifies Zoetis’ dedication to innovation in parasiticides and builds upon the 20-year trusted legacy of feline Revolution, which veterinarians have consistently made the number one prescribed parasiticide for cats.

Broad-spectrum parasite protection is important to consider for every cat of every lifestyle, every month. Revolution Plus will provide the protection both indoor and outdoor cats need. With this unique product from Zoetis, we can now provide higher-quality care with one monthly topical dose, giving pet owners peace of mind, while protecting cats and kittens from a wide range of external and internal pests.

Revolution Plus is a simple-to-apply, quick-drying, small-volume topical solution administered once monthly. It kills fleas before they can lay eggs, kills ticks for a full month and is proven safe for cats and kittens as young as eight weeks of age.

Revolution Plus is available at any of our locations and at our online stores.

About Revolution Plus

Revolution Plus is a quick-drying, small-volume topical solution that protects against fleas (Ctenocephalides felis), ticks (Black-legged or deer tick (Ixodes scapularis), Gulf Coast tick (Amblyomma maculatum) and American dog tick (Dermacentor variabilis)), ear mites (Otodectes cynotis), roundworms (Toxocara cati), hookworms (Ancylostoma tubaeforme), and heartworms (Dirofilaria immitis) for cats and kittens as young as eight weeks of age and weighing 2.8 pounds or greater.


The safe use of Revolution Plus has not been established in kittens less than 8 weeks old or in breeding, pregnant or lactating cats. Reported side effects in clinical trials included lethargy and anorexia. Use with caution in cats with a history of neurologic disorders. Sarolaner, one of the ingredients in Revolution Plus, is a member of the isoxazoline class, which has been associated with adverse reactions such as tremors, ataxia, and seizures. Reactions have occurred in cats with or without a history of neurologic disorders. In humans, Revolution Plus may be irritating to skin and eyes. See full Prescribing Information at www.zoetisUS.com/RevolutionPlusPI.

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