Also known as feline distemper, feline panleukopenia is a highly contagious, often fatal disease of cats. The disease is caused by a parvovirus transmitted by contact with infected cats, their feces or environmental contamination. The virus is highly resistant and capable of surviving in the environment for months. Kittens without prior vaccination or exposure are most susceptible. Signs of acute infection include fever, anorexia, vomiting, diarrhea, dehydration, abdominal pain, tremors and incoordination.